Role of Protein Misfolding and Proteostasis Deficiency in Protein Misfolding Diseases and Aging

The misfolding, aggregation, and tissue accumulation of proteins are common events in diverse chronic diseases, known as protein misfolding disorders. Many of these diseases are associated with aging, but the mechanism for this connection is unknown. Recent evidence has shown that the formation and...

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Bibliographic Details
Main Authors: Karina Cuanalo-Contreras, Abhisek Mukherjee, Claudio Soto
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2013/638083