mGlu3 receptor regulates microglial cell reactivity in neonatal rats

Abstract Background Perinatal inflammation is a key factor of brain vulnerability in neonates born preterm or with intra-uterine growth restriction (IUGR), two leading conditions associated with brain injury and responsible for neurocognitive and behavioral disorders. Systemic inflammation is recogn...

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Bibliographic Details
Main Authors: Manuela Zinni, Jérôme Mairesse, Julien Pansiot, Francesco Fazio, Luisa Iacovelli, Nico Antenucci, Rosamaria Orlando, Ferdinando Nicoletti, Daniel Vaiman, Olivier Baud
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-020-02049-z