Phosphorylation of the WH2 domain in yeast Las17/WASP regulates G-actin binding and protein function during endocytosis

Abstract Actin nucleation is the key rate limiting step in the process of actin polymerization, and tight regulation of this process is critical to ensure actin filaments form only at specific times and at defined regions of the cell. WH2 domains are short sequence motifs found in many different act...

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Bibliographic Details
Main Authors: J. J. Tyler, I. I. Smaczynska-de Rooij, L. Abugharsa, J. S. Palmer, L. P. Hancock, E. G. Allwood, K. R. Ayscough
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88826-z