Altered Theta Oscillations and Aberrant Cortical Excitatory Activity in the 5XFAD Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is an age-related neurodegenerative disorder characterized by impairment of memory function. The 5XFAD mouse model was analyzed and compared with wild-type (WT) controls for aberrant cortical excitability and hippocampal theta oscillations by using simultaneous video-electro...

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Bibliographic Details
Main Authors: Magdalena Elisabeth Siwek, Ralf Müller, Christina Henseler, Astrid Trog, Andreas Lundt, Carola Wormuth, Karl Broich, Dan Ehninger, Marco Weiergräber, Anna Papazoglou
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2015/781731