Dose-related estrogen effects on gene expression in fetal mouse prostate mesenchymal cells.

Developmental exposure of mouse fetuses to estrogens results in dose-dependent permanent effects on prostate morphology and function. Fetal prostatic mesenchyme cells express estrogen receptor alpha (ERα) and androgen receptors and convert stimuli from circulating estrogens and androgens into paracr...

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Bibliographic Details
Main Authors: Julia A Taylor, Catherine A Richter, Atsuko Suzuki, Hajime Watanabe, Taisen Iguchi, Kathryn R Coser, Toshihiro Shioda, Frederick S vom Saal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3483223?pdf=render