Dose-related estrogen effects on gene expression in fetal mouse prostate mesenchymal cells.
Developmental exposure of mouse fetuses to estrogens results in dose-dependent permanent effects on prostate morphology and function. Fetal prostatic mesenchyme cells express estrogen receptor alpha (ERα) and androgen receptors and convert stimuli from circulating estrogens and androgens into paracr...
Main Authors: | Julia A Taylor, Catherine A Richter, Atsuko Suzuki, Hajime Watanabe, Taisen Iguchi, Kathryn R Coser, Toshihiro Shioda, Frederick S vom Saal |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3483223?pdf=render |
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