Role of NLRP3 Inflammasome Activation in Obesity-Mediated Metabolic Disorders

Role of NLRP3 Inflammasome Activation in Obesity-Mediated Metabolic Disorders

NLRP3 inflammasome is one of the multimeric protein complexes of the nucleotide-binding domain, leucine-rich repeat (NLR)-containing pyrin and HIN domain family (PYHIN). When activated, NLRP3 inflammasome triggers the release of pro-inflammatory interleukins (IL)-1β and IL-18, an essential step in i...

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Bibliographic Details
Main Authors: Kaiser Wani, Hind AlHarthi, Amani Alghamdi, Shaun Sabico, Nasser M. Al-Daghri
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Environmental Research and Public Health
Subjects:
NLRP3 inflammasome
metabolic stress
insulin resistance
diabetes
obesity
Online Access:https://www.mdpi.com/1660-4601/18/2/511

Internet

https://www.mdpi.com/1660-4601/18/2/511

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