Short term efficacy and safety of low dose tolvaptan in patients with acute decompensated heart failure with hyponatremia: a prospective observational pilot study from a single center in South India

Background: In acute decompensated heart failure (ADHF), diuretic use, the mainstay therapy for congestion, is associated with electrolyte abnormalities and worsening renal function. Vasopressin mediates fluid retention in heart failure. In contrast to diuretics, the vasopressin antagonist tolvaptan...

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Main Authors: Soumya Patra, Basant Kumar, Kaushal K Harlalka, Apoorva Jain, H M Bhanuprakash, K S Sadananda, Harsha Basappa, K Santhosh, K S Rajith, K S Bharathi, C N Manjunath
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Heart Views
Subjects:
Online Access:http://www.heartviews.org/article.asp?issn=1995-705X;year=2014;volume=15;issue=1;spage=1;epage=5;aulast=Patra