The Ovarian Transcriptome of Reproductively Aged Multiparous Mice: Candidate Genes for Ovarian Cancer Protection

In middle-aged women, the decline of ovarian follicle reserve below a critical threshold marks menopause, leading to hormonal, inflammatory, and metabolic changes linked to disease. The highest incidence and mortality of sporadic ovarian cancer (OC) occur at post-menopause, while OC risk is reduced...

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Bibliographic Details
Main Authors: Ulises Urzúa, Carlos Chacón, Maximiliano Norambuena, Luis Lizama, Sebastián Sarmiento, Esther Asaki, John I Powell, Sandra Ampuero
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Biomolecules
Subjects:
age
Online Access:https://www.mdpi.com/2218-273X/10/1/113