Hyaluronidases and hyaluronan synthases expression is inversely correlated with malignancy in lung/bronchial pre-neoplastic and neoplastic lesions, affecting prognosis

Hyaluronidases and hyaluronan synthases expression is inversely correlated with malignancy in lung/bronchial pre-neoplastic and neoplastic lesions, affecting prognosis

We collected a series of 136 lung/bronchial and 56 matched lung parenchyma tissue samples from patients who underwent lung/bronchial biopsies and presented invasive carcinoma after lung surgery. The lung/bronchial samples included basal cell hyperplasia, squamous metaplasia, moderate dysplasia, aden...

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Bibliographic Details
Main Authors: V.K. de Sá, T.P. Rocha, AL. Moreira, F.A. Soares, T. Takagaki, L. Carvalho, A.G. Nicholson, V.L. Capelozzi
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2015-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Hyaluronidases and hyaluronan synthases
Lung cancer
Pre-neoplastic lung/bronchial lesions
Immunohistochemistry
Morphometry
Prognosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001101039&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001101039&lng=en&tlng=en

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