A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in Han Chinese.

A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in Han Chinese.

With numbers of common variants identified mainly through genome-wide association studies (GWASs), there is great interest in incorporating the findings into screening individuals at high risk of psoriasis. The purpose of this study is to establish genetic prediction models and evaluate its discrimi...

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Bibliographic Details
Main Authors: Xianyong Yin, Hui Cheng, Yan Lin, Nathan E Wineinger, Fusheng Zhou, Yujun Sheng, Chao Yang, Pan Li, Feng Li, Changbing Shen, Sen Yang, Nicholas J Schork, Xuejun Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4416725?pdf=render

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http://europepmc.org/articles/PMC4416725?pdf=render

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