Down-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis
Breast cancer: Trapping tumors in place Drugs that inhibit two protein-digesting enzymes could offer potent protection against tumor growth and metastasis in an aggressive form of breast cancer. “Triple-negative breast cancer” (TNBC), which lacks three common tumor biomarkers, carries a poor prognos...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-09-01
|
| Series: | Experimental and Molecular Medicine |
| Online Access: | https://doi.org/10.1038/s12276-018-0135-9 |