Down-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis

Down-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis

Breast cancer: Trapping tumors in place Drugs that inhibit two protein-digesting enzymes could offer potent protection against tumor growth and metastasis in an aggressive form of breast cancer. “Triple-negative breast cancer” (TNBC), which lacks three common tumor biomarkers, carries a poor prognos...

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Bibliographic Details
Main Authors: Jaya Gautam, Suhrid Banskota, Hyunji Lee, Yu-Jeong Lee, Yong Hyun Jeon, Jung-Ae Kim, Byeong-Seon Jeong
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0135-9

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