Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression

Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression

Abstract Background The wide variety of specialized permissive and repressive mechanisms by which germ cells regulate developmental gene expression are not well understood genome-wide. Isolation of germ cells with high integrity and purity from living animals is necessary to address these open quest...

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Bibliographic Details
Main Authors: Mei Han, Guifeng Wei, Catherine E. McManus, LaDeana W. Hillier, Valerie Reinke
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Genomics
Subjects:
C. elegans
Germ cells
Gene expression
Genomics
Method development
Online Access:http://link.springer.com/article/10.1186/s12864-019-5893-9

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http://link.springer.com/article/10.1186/s12864-019-5893-9

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