Copy Number Alteration Profile Provides Additional Prognostic Value for Acute Lymphoblastic Leukemia Patients Treated on BFM Protocols

Copy Number Alteration Profile Provides Additional Prognostic Value for Acute Lymphoblastic Leukemia Patients Treated on BFM Protocols

We present our data of a novel proposed CNA-profile risk-index, applied on a Greek ALLIC-BFM-treated cohort, aiming at further refining genomic risk-stratification. Eighty-five of 227 consecutively treated ALL patients were analyzed for the copy-number-status of eight genes (IKZF1/CDKN2A/2B/PAR1/BTG...

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Bibliographic Details
Main Authors: Μirella Αmpatzidou, Lina Florentin, Vassilios Papadakis, Georgios Paterakis, Marianna Tzanoudaki, Dimitra Bouzarelou, Stefanos I. Papadhimitriou, Sophia Polychronopoulou
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
acute lymphoblastic leukemia
child
genetics
MLPA
copy number alterations (CNAs)
risk stratification
Online Access:https://www.mdpi.com/2072-6694/13/13/3289

Internet

https://www.mdpi.com/2072-6694/13/13/3289

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