Regulation of Hepatic UGT2B15 by Methylation in Adults of Asian Descent
The hepatic uridine 5′-diphosphate-glucuronosyl transferases (UGTs) are critical for detoxifying endo- and xenobiotics. Since UGTs are also dynamically responsive to endogenous and exogenous stimuli, we examined whether epigenetic DNA methylation can regulate hepatic UGT expression and differential...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-01-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4923/10/1/6 |