Oestrogens Downregulate Tissue Factor Pathway Inhibitor through Oestrogen Response Elements in the 5'-Flanking Region.

Oestrogens Downregulate Tissue Factor Pathway Inhibitor through Oestrogen Response Elements in the 5'-Flanking Region.

Oestrogens influence the pathology and development of hormone-sensitive breast cancers. Tissue factor pathway inhibitor (TFPI) has been shown to be associated with breast cancer pathogenesis. Recently, we found TFPI mRNA levels to be significantly reduced by oestrogens in a breast cancer cell line (...

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Bibliographic Details
Main Authors: Huda Omar Ali, Benedicte Stavik, Christiane Filion Myklebust, Elisabeth Andersen, Anders E A Dahm, Nina Iversen, Per Morten Sandset, Grethe Skretting
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0152114

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https://doi.org/10.1371/journal.pone.0152114

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