Mechanism of the blood pressure-lowering effect of sodium-glucose cotransporter 2 inhibitors in obese patients with type 2 diabetes

Mechanism of the blood pressure-lowering effect of sodium-glucose cotransporter 2 inhibitors in obese patients with type 2 diabetes

Abstract Background Sodium-glucose cotransporter 2 (SGLT2) inhibitors are reported to have BP-lowering effect in addition to blood glucose-lowering effect, however, its mechanism is still unknown. This study aimed to investigate the mechanism of blood pressure (BP) lowering effects of SGLT2 inhibito...

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Bibliographic Details
Main Authors: Shin Kawasoe, Yukiko Maruguchi, Shoko Kajiya, Hitoshi Uenomachi, Masaaki Miyata, Mariko Kawasoe, Takuro Kubozono, Mitsuru Ohishi
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Pharmacology and Toxicology
Subjects:
Blood pressure
Natriuresis
Osmotic diuresis
SGLT2 inhibitor
Type 2 diabetes
Online Access:http://link.springer.com/article/10.1186/s40360-017-0125-x

Internet

http://link.springer.com/article/10.1186/s40360-017-0125-x

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