The effective transfection of a low dose of negatively charged drug-loaded DNA-nanocarriers into cancer cells via scavenger receptors

The effective transfection of a low dose of negatively charged drug-loaded DNA-nanocarriers into cancer cells via scavenger receptors

DNA-nanotechnology-based nano-architecture scaffolds based on circular strands were designed in the form of DNA-nanowires (DNA-NWs) as a polymer of DNA-triangles. Circularizing a scaffold strand (84-NT) was the critical step followed by annealing with various staple strands to make stiff DNA-triangl...

Full description

Bibliographic Details
Main Authors: Mirza Muhammad Faran Ashraf Baig, Chengfei Zhang, Muhammad Furqan Akhtar, Ammara Saleem, Jahanzeb Mudassir
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Cisplatin (CPT)
DNA-nanowires (DNA-NWs)
HepG2 resistant cancer cells
Scavenger receptors
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177920310741

Internet

http://www.sciencedirect.com/science/article/pii/S2095177920310741

Similar Items