Renoprotective Effects of Alpha-1 Antitrypsin against Tacrolimus-Induced Renal Injury

Renoprotective Effects of Alpha-1 Antitrypsin against Tacrolimus-Induced Renal Injury

The protective effects of alpha-1 antitrypsin (AAT) in tacrolimus (TAC)-induced renal injury was evaluated in a rat model. The TAC group rats were subcutaneously injected with 2 mg/kg TAC every day for four weeks. The TAC with AAT group was cotreated with daily subcutaneous injections of TAC and int...

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Bibliographic Details
Main Authors: Jeong-Hoon Lim, Eun-Joo Oh, Se-Hyun Oh, Hee-Yeon Jung, Ji-Young Choi, Jang-Hee Cho, Sun-Hee Park, Yong-Lim Kim, Chan-Duck Kim
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
alpha-1 antitrypsin
tacrolimus-induced renal injury
fibrosis
inflammation
apoptosis
Online Access:https://www.mdpi.com/1422-0067/21/22/8628

Internet

https://www.mdpi.com/1422-0067/21/22/8628

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