Design, synthesis, antimicrobial and cytotoxicity study on human colorectal carcinoma cell line of new 4,4′-(1,4-phenylene)bis(pyrimidin-2-amine) derivatives

Design, synthesis, antimicrobial and cytotoxicity study on human colorectal carcinoma cell line of new 4,4′-(1,4-phenylene)bis(pyrimidin-2-amine) derivatives

Abstract Background Pyrimidine molecules attracted organic chemists very much due to their biological and chemotherapeutic importance. Their related fused heterocycles are of interest as potential bioactive molecules so, we have designed and prepared a new class of 4,4′-(1,4-phenylene)bis(pyrimidin-...

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Bibliographic Details
Main Authors: Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani, Syed Adnan Ali Shah, Balasubramanian Narasimhan
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Chemistry Central Journal
Subjects:
Pyrimidine molecules
Design
Synthesis
Antimicrobial
Cytotoxicity
HCT116
Online Access:http://link.springer.com/article/10.1186/s13065-018-0440-3

Internet

http://link.springer.com/article/10.1186/s13065-018-0440-3

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