MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection.

MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection.

Mucosal-associated invariant T (MAIT) cells can recognize and respond to some bacterially infected cells. Several in vitro and in vivo models of Mycobacterium tuberculosis (Mtb) infection suggest that MAIT cells can contribute to control of Mtb, but these studies are often cross-sectional and use pe...

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Bibliographic Details
Main Authors: Amy L Ellis, Alexis J Balgeman, Erica C Larson, Mark A Rodgers, Cassaundra Ameel, Tonilynn Baranowski, Nadean Kannal, Pauline Maiello, Jennifer A Juno, Charles A Scanga, Shelby L O'Connor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008585

Internet

https://doi.org/10.1371/journal.ppat.1008585

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