Mechanisms involved in the vasorelaxant effects produced by the acute application of amfepramone in vitro to rat aortic rings

Mechanisms involved in the vasorelaxant effects produced by the acute application of amfepramone in vitro to rat aortic rings

Amfepramone (diethylpropion) is an appetite-suppressant drug used for the treatment of overweight and obesity. It has been suggested that the systemic and central activity of amfepramone produces cardiovascular effects such as transient ischemic attacks and primary pulmonary hypertension. However, i...

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Bibliographic Details
Main Authors: J.S. López-Canales, J. Lozano-Cuenca, E. Muãoz-Islas, J.C. Aguilar-Carrasco, O.A. López-Canales, R.M. López-Mayorga, E.F. Castillo-Henkel, I. Valencia-Hernández, C. Castillo-Henkel
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2015-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Cardiovascular pharmacology
Amfepramone
Obesity
Rat aorta
Nitric oxide
Potassium channels
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000600537&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000600537&lng=en&tlng=en

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