CRP is an activator of Yersinia pestis biofilm formation that operates via a mechanism involving gmhA and waaAE-coaD.

CRP is an activator of Yersinia pestis biofilm formation that operates via a mechanism involving gmhA and waaAE-coaD.

gmhA encodes a phosphoheptose isomerase that catalyzes the biosynthesis of heptose, a conserved component of lipopolysaccharide (LPS). GmhA plays an important role in Yersinia pestis biofilm blockage in the flea gut. waaA, waaE, and coaD constitute a three-gene operon waaAE-coaD in Y. pestis. waaA e...

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Bibliographic Details
Main Authors: Lei eLiu, Haihong eFang, Huiying eYang, Yiquan eZhang, Yanping eHan, Dongsheng eZhou, Ruifu eYang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Microbiology
Subjects:
Yersinia pestis
Biofilm
crp
gmhA
waaAE-coaD
phoPQ-YPO1632
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00295/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00295/full

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