Gauchos and ochos: a Wee1-Cdk tango regulating mitotic entry
<p>Abstract</p> <p>The kinase Wee1 has been recognized for a quarter century as a key inhibitor of Cyclin dependent kinase 1 (Cdk1) and mitotic entry in eukaryotes. Nonetheless, Wee1 regulation is not well understood and its large amino-terminal regulatory domain (NRD) has remained...
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| Format: | Article |
| Language: | English |
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BMC
2010-05-01
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| Series: | Cell Division |
| Online Access: | http://www.celldiv.com/content/5/1/12 |