Update on the Protective Molecular Pathways Improving Pancreatic Beta-Cell Dysfunction

The primary function of pancreatic beta-cells is to produce and release insulin in response to increment in extracellular glucose concentrations, thus maintaining glucose homeostasis. Deficient beta-cell function can have profound metabolic consequences, leading to the development of hyperglycemia a...

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Bibliographic Details
Main Authors: Alessandra Puddu, Roberta Sanguineti, François Mach, Franco Dallegri, Giorgio Luciano Viviani, Fabrizio Montecucco
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2013/750540