Gut-associated IgA+ immune cells regulate obesity-related insulin resistance

Gut-associated IgA+ immune cells regulate obesity-related insulin resistance

The effect of diet-induced obesity on intestinal B cell populations is not well understood despite emerging evidence of a critical role for the intestinal immune system in contributing to insulin resistance. Here, the authors show important functions of IgA in regulating metabolic disease and for in...

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Bibliographic Details
Main Authors: Helen Luck, Saad Khan, Justin H. Kim, Julia K. Copeland, Xavier S. Revelo, Sue Tsai, Mainak Chakraborty, Kathleen Cheng, Yi Tao Chan, Mark K. Nøhr, Xavier Clemente-Casares, Marie-Christine Perry, Magar Ghazarian, Helena Lei, Yi-Hsuan Lin, Bryan Coburn, Allan Okrainec, Timothy Jackson, Susan Poutanen, Herbert Gaisano, Johane P. Allard, David S. Guttman, Margaret E. Conner, Shawn Winer, Daniel A. Winer
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11370-y

Internet

https://doi.org/10.1038/s41467-019-11370-y

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