Up-regulation of microRNA-126 may contribute to pathogenesis of ulcerative colitis via regulating NF-kappaB inhibitor IκBα.

Up-regulation of microRNA-126 may contribute to pathogenesis of ulcerative colitis via regulating NF-kappaB inhibitor IκBα.

MicroRNAs (miRNAs) are important post-transcriptional regulators. Altered expression of miRNAs has recently demonstrated association with human ulcerative colitis (UC). In this study, we attempted to elucidate the roles of miR-126 in the pathogenesis of UC.Expression of miR-126, miR-21, miR-375 and...

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Bibliographic Details
Main Authors: Xiao Feng, Hao Wang, Shicai Ye, Jiaxi Guan, Wenkai Tan, Si Cheng, Guoli Wei, Weiyun Wu, Feng Wu, Yu Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3532399?pdf=render

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http://europepmc.org/articles/PMC3532399?pdf=render

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