Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling

Meiotically arrested oocytes retain transcriptional ability despite chromosome condensation. Here, the authors show that Drosophilaoocytes regulate meiotic transcription and chromatin remodelling through the programming, in early oogenesis, of an extremely diversified epigenome.

Bibliographic Details
Main Authors: Paulo Navarro-Costa, Alicia McCarthy, Pedro Prudêncio, Christina Greer, Leonardo G. Guilgur, Jörg D. Becker, Julie Secombe, Prashanth Rangan, Rui G. Martinho
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12331