Retinoic acid modulates intrahippocampal levels of corticosterone in middle-aged mice: consequences on hippocampal plasticity and contextual memory.

Retinoic acid modulates intrahippocampal levels of corticosterone in middle-aged mice: consequences on hippocampal plasticity and contextual memory.

It is now established that vitamin A and its derivatives, retinoic acid (RA), are required for cognitive functions in adulthood. RA hyposignaling and hyperactivity of glucocorticoid (GC) pathway appear concomitantly during ageing and would contribute to the deterioration of hippocampal synaptic plas...

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Bibliographic Details
Main Authors: Damien eBonhomme, Véronique ePallet, Gaelle eDominguez, Laure eServant, Nadia eHenkous, Pauline eLafenetre, Paul eHigueret, Daniel eBéracochéa, Katia eTouyarot
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
Corticosterone
Memory
Vitamin A
Retinoic acid
Hippocampal plasticity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00006/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00006/full

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