Foot-and-Mouth Disease Virus Counteracts on Internal Ribosome Entry Site Suppression by G3BP1 and Inhibits G3BP1-Mediated Stress Granule Assembly via Post-Translational Mechanisms

Foot-and-Mouth Disease Virus Counteracts on Internal Ribosome Entry Site Suppression by G3BP1 and Inhibits G3BP1-Mediated Stress Granule Assembly via Post-Translational Mechanisms

Foot-and-mouth disease (FMD) is a highly contagious, severe viral illness notifiable to the World Organization for Animal Health. The causative agent, FMD virus (FMDV), replicates rapidly and efficiently inhibits host translation and the innate immune response for it has developed multiple tactics t...

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Bibliographic Details
Main Authors: Xu Ye, Ting Pan, Dang Wang, Liurong Fang, Jun Ma, Xinyu Zhu, Yanling Shi, Keshan Zhang, Haixue Zheng, Huanchun Chen, Kui Li, Shaobo Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
foot-and-mouth disease virus
phosphoproteomics
G3BP stress granule assembly factor 1
internal ribosome entry site
innate immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01142/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01142/full

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