The bacterial protein azurin impairs invasion and FAK/Src signaling in P-cadherin-overexpressing breast cancer cell models.

P-cadherin overexpression occurs in about 30% of all breast carcinomas, being a poor prognostic factor for breast cancer patients. In a cellular background of wild-type E-cadherin, we have previously shown that its expression promotes invasion, motility and migration of breast cancer cells due to th...

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Bibliographic Details
Main Authors: Nuno Bernardes, Ana Sofia Ribeiro, Sofia Abreu, Bruna Mota, Rute G Matos, Cecilia M Arraiano, Raquel Seruca, Joana Paredes, Arsenio M Fialho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3716805?pdf=render