Dietary intake of genistein suppresses hepatocellular carcinoma through AMPK-mediated apoptosis and anti-inflammation

Dietary intake of genistein suppresses hepatocellular carcinoma through AMPK-mediated apoptosis and anti-inflammation

Abstract Background Women have a lower risk of hepatocellular carcinoma (HCC) than men, and the decreased possibility of HCC in women is thought to depend on estrogen levels. As a soybean-isoflavone product, genistein has estrogenic activity in various reproductive tissues, because it mimics 17β-est...

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Bibliographic Details
Main Authors: Sang R. Lee, Sun Woo Kwon, Young Ho Lee, Pelin Kaya, Jong Min Kim, Changhwan Ahn, Eui-Man Jung, Geun-Shik Lee, Beum-Soo An, Eui-Bae Jeung, Bae-keun Park, Eui-Ju Hong
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Cancer
Subjects:
HCC
Genistein
AMPK
Inflammation
Apoptosis
Phytoestrogen
Online Access:http://link.springer.com/article/10.1186/s12885-018-5222-8

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http://link.springer.com/article/10.1186/s12885-018-5222-8

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