Guanylate-binding protein-1 is a potential new therapeutic target for triple-negative breast cancer

Guanylate-binding protein-1 is a potential new therapeutic target for triple-negative breast cancer

Abstract Background Triple-negative breast cancer (TNBC) is characterized by a lack of estrogen and progesterone receptor expression (ESR and PGR, respectively) and an absence of human epithelial growth factor receptor (ERBB2) amplification. Approximately 15–20% of breast malignancies are TNBC. Pati...

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Bibliographic Details
Main Authors: Melissa Quintero, Douglas Adamoski, Larissa Menezes dos Reis, Carolline Fernanda Rodrigues Ascenção, Krishina Ratna Sousa de Oliveira, Kaliandra de Almeida Gonçalves, Marília Meira Dias, Marcelo Falsarella Carazzolle, Sandra Martha Gomes Dias
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Cancer
Subjects:
Breast cancer
Triple-negative breast cancer
Gene expression
RNA-Seq
Transcriptomics
Therapeutic target
Online Access:http://link.springer.com/article/10.1186/s12885-017-3726-2

Internet

http://link.springer.com/article/10.1186/s12885-017-3726-2

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