Weight-gain induced changes in renal perfusion assessed by contrast-enhanced ultrasound precede increases in urinary protein excretion suggestive of glomerular and tubular injury and normalize after weight-loss in dogs.

Weight-gain induced changes in renal perfusion assessed by contrast-enhanced ultrasound precede increases in urinary protein excretion suggestive of glomerular and tubular injury and normalize after weight-loss in dogs.

Early detection of obesity-related glomerulopathy in humans is challenging as it might not be detected by routine biomarkers of kidney function. This study's aim was to use novel kidney biomarkers and contrast-enhanced ultrasound (CEUS) to evaluate the effect of obesity development and weight-l...

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Bibliographic Details
Main Authors: Daisy J X Liu, Emmelie Stock, Bart J G Broeckx, Sylvie Daminet, Evelyne Meyer, Joris R Delanghe, Siska Croubels, Mathias Devreese, Patrick Nguyen, Evelien Bogaerts, Myriam Hesta, Katrien Vanderperren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231662

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https://doi.org/10.1371/journal.pone.0231662

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