Sexually-transmitted/founder HIV-1 cannot be directly predicted from plasma or PBMC-derived viral quasispecies in the transmitting partner.

OBJECTIVE: Characterization of HIV-1 sequences in newly infected individuals is important for elucidating the mechanisms of viral sexual transmission. We report the identification of transmitted/founder viruses in eight pairs of HIV-1 sexually-infected patients enrolled at the time of primary infect...

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Bibliographic Details
Main Authors: Pierre Frange, Laurence Meyer, Matthieu Jung, Cecile Goujard, David Zucman, Sylvie Abel, Patrick Hochedez, Marine Gousset, Olivier Gascuel, Christine Rouzioux, Marie-Laure Chaix, ANRS PRIMO Cohort Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706485?pdf=render