CD4+CD8+ T-Lymphocytes in Xenogeneic and Human Graft-versus-Host Disease

CD4+CD8+ T-Lymphocytes in Xenogeneic and Human Graft-versus-Host Disease

Mechanisms driving acute graft-versus-host disease (aGVHD) onset in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) are still poorly understood. To provide a detailed characterization of tissue-infiltrating T lymphocytes (TL) and search for eventual site-specific s...

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Bibliographic Details
Main Authors: Kutaiba Alhaj Hussen, David Michonneau, Vincent Biajoux, Seydou Keita, Laetitia Dubouchet, Elisabeth Nelson, Niclas Setterblad, Helene Le Buanec, Jean-David Bouaziz, Fabien Guimiot, Gérard Socié, Bruno Canque
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
allogeneic hematopoietic stem cell transplantation
graft-versus-host disease
xenograft mouse model
CD4+CD8+ T lymphocytes
immunoregulatory diversion
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.579776/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.579776/full

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