Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation

<p>Abstract</p> <p>Background</p> <p>Protein aggregation is a hallmark of several neurodegenerative diseases including Huntington's disease and Parkinson's disease. Proteins containing long, homopolymeric stretches of glutamine are especially prone to form agg...

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Bibliographic Details
Main Authors: Caldwell Guy A, Caldwell Kim A, Hajjar Connie, Sharma Pratima, Howard Rebecca A, du Breuil Rusla, Moore Rhonda, Boyd Lynn
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/8/32