Low-cost cross-taxon enrichment of mitochondrial DNA using in-house synthesised RNA probes.

Low-cost cross-taxon enrichment of mitochondrial DNA using in-house synthesised RNA probes.

Hybridization capture with in-solution oligonucleotide probes has quickly become the preferred method for enriching specific DNA loci from degraded or ancient samples prior to high-throughput sequencing (HTS). Several companies synthesize sets of probes for in-solution hybridization capture, but the...

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Bibliographic Details
Main Authors: Stephen M Richards, Nelli Hovhannisyan, Matthew Gilliham, Joshua Ingram, Birgitte Skadhauge, Holly Heiniger, Bastien Llamas, Kieren J Mitchell, Julie Meachen, Geoffrey B Fincher, Jeremy J Austin, Alan Cooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209499

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