Short-Term Relapse Quantitation as a Fully Surrogate Endpoint for Long-Term Sustained Progression of Disability in RRMS Patients Treated with Natalizumab

Time to sustained worsening in the expanded disability status scale as the standard for evaluating the accumulation of disability has been used as a measure of clinical efficacy in many relapsing-remitting multiple sclerosis (RRMS) clinical trials. However, this measurement usually requires a large...

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Bibliographic Details
Main Authors: Y. C. Wang, A. Sandrock, J. R. Richert, L. Meyerson, X. Miao
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Neurology Research International
Online Access:http://dx.doi.org/10.1155/2011/195831