A Sensitive Method for Detecting Peptide-specific CD4+ T Cell Responses in Peripheral Blood from Patients with Myasthenia Gravis

A Sensitive Method for Detecting Peptide-specific CD4+ T Cell Responses in Peripheral Blood from Patients with Myasthenia Gravis

Myasthenia gravis (MG) is an autoimmune neurological disorder typified by skeletal muscle fatigue and most often production of autoantibodies against the nicotinic acetylcholine receptor (AChR). The present study was undertaken to assess the extent of AChR-peptide recognition in MG patients using co...

Full description

Bibliographic Details
Main Authors: Sapna Sharma, Clas Malmeström, Christopher Lindberg, Sarah Meisel, Karin Schön, Martina Verolin, Nils Yngve Lycke
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
myasthenia gravis
acetylcholine receptor
autoimmune disease
dendritic cells
CD4+ T cells
peripheral blood and peptide
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01370/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01370/full

Similar Items