Immunological Distinctions between Acellular and Whole-Cell Pertussis Immunizations of Baboons Persist for at Least One Year after Acellular Vaccine Boosting

Immunological Distinctions between Acellular and Whole-Cell Pertussis Immunizations of Baboons Persist for at Least One Year after Acellular Vaccine Boosting

While both whole-cell (wP) and acellular pertussis (aP) vaccines have been highly effective at reducing the global pertussis disease burden, there are concerns that compared to wP vaccination, the immune responses to aP vaccination may wane more rapidly. To gain insights into the vaccine elicited im...

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Bibliographic Details
Main Authors: Leah E. Cole, Jinrong Zhang, Kristl M. Pacheco, Philippe Lhéritier, Natalie G. Anosova, Julie Piolat, Lingyi Zheng, Nathalie Reveneau
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Vaccines
Subjects:
pertussis
baboon model
immunological profile
whole cell pertussis vaccine
acellular pertussis vaccine
Online Access:https://www.mdpi.com/2076-393X/8/4/729

Internet

https://www.mdpi.com/2076-393X/8/4/729

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