Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins

<p>Abstract</p> <p>Background</p> <p>Pregnancy associated malaria is a severe clinical syndrome associated with sequestration of <it>Plasmodium falciparum</it>-infected erythrocytes in the placenta. Placental binding is mediated by VAR2CSA, which adheres to...

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Bibliographic Details
Main Authors: Hathaway Marianne J, Cartwright Megan M, Avril Marion, Smith Joseph D
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/10/1/36