Evidence-based annotation of gene function in Shewanella oneidensis MR-1 using genome-wide fitness profiling across 121 conditions.

Evidence-based annotation of gene function in Shewanella oneidensis MR-1 using genome-wide fitness profiling across 121 conditions.

Most genes in bacteria are experimentally uncharacterized and cannot be annotated with a specific function. Given the great diversity of bacteria and the ease of genome sequencing, high-throughput approaches to identify gene function experimentally are needed. Here, we use pools of tagged transposon...

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Bibliographic Details
Main Authors: Adam Deutschbauer, Morgan N Price, Kelly M Wetmore, Wenjun Shao, Jason K Baumohl, Zhuchen Xu, Michelle Nguyen, Raquel Tamse, Ronald W Davis, Adam P Arkin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3219624?pdf=render

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http://europepmc.org/articles/PMC3219624?pdf=render

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