Ischemic postconditioning-mediated miRNA-21 protects against cardiac ischemia/reperfusion injury via PTEN/Akt pathway.

BACKGROUND: Ischemic postconditioning (IPost) protects the reperfused heart from infarction which has drawn much attention recently. However, studies to date have rarely investigated the role of microRNAs (miRNAs) in IPost. The aims of this study were to investigate whether miR-21 is involved in the...

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Bibliographic Details
Main Authors: Yingfeng Tu, Lin Wan, Yuhua Fan, Kezheng Wang, Lihong Bu, Tao Huang, Zhen Cheng, Baozhong Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3789724?pdf=render