Dexamethasone does not ameliorate gliosis in a mouse model of neurodegenerative disease

Dexamethasone does not ameliorate gliosis in a mouse model of neurodegenerative disease

Prolonged neuroinflammation is a driving force for neurodegenerative disease, and agents against inflammatory responses are regarded as potential treatment strategies. Here we aimed to evaluate the prevention effects on gliosis by dexamethasone (DEX), an anti-inflammation drug. We used DEX to treat...

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Bibliographic Details
Main Authors: Xiaolian Ye, Gang Zou, Jinxing Hou, Huiru Bi, Cuihua Zhou, Runmin Wang, Yun Xu, Chun Wang, Guiquan Chen, Zhenyu Yin, Jinping Zhang, Chaoli Huang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Neurodegeneration
Neuroinflammation
Dexamethasone
Neuron
Synaptic loss
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580820301278

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http://www.sciencedirect.com/science/article/pii/S2405580820301278

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