NET23/STING promotes chromatin compaction from the nuclear envelope.

Changes in the peripheral distribution and amount of condensed chromatin are observed in a number of diseases linked to mutations in the lamin A protein of the nuclear envelope. We postulated that lamin A interactions with nuclear envelope transmembrane proteins (NETs) that affect chromatin structur...

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Bibliographic Details
Main Authors: Poonam Malik, Nikolaj Zuleger, Jose I de las Heras, Natalia Saiz-Ros, Alexandr A Makarov, Vassiliki Lazou, Peter Meinke, Martin Waterfall, David A Kelly, Eric C Schirmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4227661?pdf=render