IRTKS Promotes Insulin Signaling Transduction through Inhibiting SHIP2 Phosphatase Activity

IRTKS Promotes Insulin Signaling Transduction through Inhibiting SHIP2 Phosphatase Activity

Insulin signaling is mediated by a highly integrated network that controls glucose metabolism, protein synthesis, cell growth, and differentiation. Our previous work indicates that the insulin receptor tyrosine kinase substrate (IRTKS), also known as BAI1-associated protein 2-like 1 (BAIAP2L1), is a...

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Bibliographic Details
Main Authors: Chongchao Wu, Xiaofang Cui, Liyu Huang, Xueying Shang, Binghao Wu, Na Wang, Kunyan He, Zeguang Han
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
insulin pathway
IRTKS
SHIP2
PI(3,4,5)P<sub>3</sub>
Online Access:https://www.mdpi.com/1422-0067/20/11/2834

Internet

https://www.mdpi.com/1422-0067/20/11/2834

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