Nanoparticle-coated organic-inorganic microparticles: experimental design and gastrointestinal tolerance evaluation

The influences of the spray-drying parameters and the type of nanoparticles (nanocapsules or nanospheres) on the characteristics of nanoparticle-coated diclofenac-loaded microparticles were investigated by using a factorial design 3². Gastrointestinal tolerance following oral administration in rats...

Full description

Bibliographic Details
Main Authors: Beck Ruy Carlos R., Haas Sandra Elisa, Guterres Silvia Stanisçuaski, Ré Maria Inês, Benvenutti Edilson V., Pohlmann Adriana Raffin
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2006-01-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422006000500019