TLR-2 activation induces regulatory T cells and long-term suppression of asthma manifestations in mice.

Asthma is a chronic inflammatory disease of the airways characterized by variable airway obstruction and airway hyperresponsiveness (AHR). The T regulatory (Treg) cell subset is critically important for the regulation of immune responses. Adoptive transfer of Treg cells has been shown to be sufficie...

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Bibliographic Details
Main Authors: Martijn C Nawijn, Alexandre C Motta, Renée Gras, Soheila Shirinbak, Hadi Maazi, Antoon J M van Oosterhout
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3564817?pdf=render